2581   AN ULTRASTRUCTURE STUDY OF SPIROGYRA AN ULTRASTRUCTURE STUDY OF SPIROGYRA Siyu Ni, Kaili Lin, Jiang Chang and Lee Chou    2007 The fine structure of three species of Spirogyra is presented, utilizing bright field, polarized light, and electron microscopes; x-ray diffraction; and autoradiographic techniques. The birefringent filament wall consists of an outer amorphous layer covering Cellulose I microfibrils in a multinet growth pattern. Vegetative cytoplasmic fine structure is typical of the Chlorophyta with the exception of karyoids which are described. Autoradiography indicated spots on the conjugating filament walls ... 查看全文

2582   NanoSIMS50 — a powerful tool to elucidate cellular localization of halogenated organic compounds NanoSIMS50 — a powerful tool to elucidate cellular localization of halogenated organic compounds Arno C. Gutleb, Jaime Freitas, Albertinka J. Murk, Steven Verhaegen, Erik Ropstad, Thomas Udelhoven,    0 Persistent organic pollutants are widely distributed in the environment and lots of toxicological data are available. However, little is known on the intracellular fate of such compounds. Here a method applying secondary ion mass spectrometry is described that can be used to visualize cellular localization of halogenated compounds and to semi-quantitatively calculate concentrations of such compounds. Of the model compounds tested, TBBPA was homogenously distribut... 查看全文

2583   Reproductive aging-associated common genetic variants and the risk of breast cancer Reproductive aging-associated common genetic variants and the risk of breast cancer Chunyan He, Daniel I Chasman, Jill Dreyfus, Shih-Jen Hwang, Rikje Ruiter, Serena Sanna, Julie E Buri    2012 Introduction  A younger age at menarche and an older age at menopause are well established risk factors for breast cancer. Recent genome-wide association studies have identified several novel genetic loci associated with these two traits. However, the association between these loci and breast cancer risk is unknown. 查看全文

2584   A statistical model of elasto-plastic asperity contact between rough surfaces A statistical model of elasto-plastic asperity contact between rough surfaces    2006 This work models statistically elasto-plastic contact between two rough surfaces using the results of a previous finite element analysis of an elasto-plastic sphere in contact with a rigid flat. The individual asperity contact model used accounts for a varying geometrical hardness effect that has recently been documented in previous works (where geometrical hardness is defined as the uniform. pressure found during fully plastic contact). The contact between real surfaces with known material and ... 查看全文

2585   Proton nuclear magnetic resonance study of human immunoglobulins G1 and their proteolytic fragments: structure of the hinge region and effects of a hinge region deletion on internal flexibility Proton nuclear magnetic resonance study of human immunoglobulins G1 and their proteolytic fragments: structure of the hinge region and effects of a hinge region deletion on internal flexibility Satoshi Endo, Yoji Arata    1985 查看全文

2586   MBE Growth of MCT on GaAs Substrates at AIM MBE Growth of MCT on GaAs Substrates at AIM J. Wenisch, D. Eich, H. Lutz, T. Schallenberg, R. Wollrab;J. Ziegler    0 Driven by the need for more efficient and cost-effective production of infrared (IR) detectors as well as the demands for novel (third-generation) device concepts, a large amount of effort has been spent on the development of molecular beam epitaxy (MBE) for fabrication of high-quality HgCdTe (MCT) layers on both CdZnTe and alternative substrates. The bulk of recent publications focuses on Si as an alternative substrate material. The intent of this paper is to hi... 查看全文

2587   Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes C. Sims-Robinson, S. Zhao, J. Hur;E. L. Feldman    0 Aims/hypothesis  Type 2 diabetes is associated with complications in the central nervous system (CNS), including learning and memory, and an increased risk for neurodegenerative diseases. The mechanism underlying this association is not understood. The aim of this study was to gain greater insight into the possible mechanisms of diabetes-induced cognitive decline. 查看全文

2588   Evaluation of multifocal visual evoked potentials in patients with Graves’ orbitopathy and subclinical optic nerve involvement Evaluation of multifocal visual evoked potentials in patients with Graves’ orbitopathy and subclinical optic nerve involvement Consuelo Pérez-Rico, Natividad Rodríguez-González, Juan Arévalo-Serrano;Román Blanco    0 Dysthyroid optic neuropathy is the most serious, although infrequent (8–10 %) complication in Graves’ orbitopathy (GO). It is known that early stages of compressive optic neuropathy may produce reversible visual field defects, suggesting axoplasmic stasis rather than ganglion cell death. This observational, cross-sectional, case–control study assessed 34 consecutive patients (65 eyes) with Graves’ hyperthyroidism and longstanding GO a... 查看全文

2589   From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases From genome-wide association studies to disease mechanisms: celiac disease as a model for autoimmune diseases Vinod Kumar, Cisca Wijmenga;Sebo Withoff    0 Celiac disease is characterized by a chronic inflammatory reaction in the intestine and is triggered by gluten, a constituent derived from grains which is present in the common daily diet in the Western world. Despite decades of research, the mechanisms behind celiac disease etiology are still not fully understood, although it is clear that both genetic and environmental factors are involved. To improve the understanding of the disease, the genetic component has ... 查看全文

2590   Models for prediction of anti- HIV-1 activity of 5-Alkyl-2-alkylamino-6-(2, 6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones using random forest, decision tree and moving average analysis Models for prediction of anti- HIV-1 activity of 5-Alkyl-2-alkylamino-6-(2, 6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones using random forest, decision tree and moving average analysis    2009 In the present study, an in silico approach using decision tree, random forest and moving average analysis has been applied to a data set comprising of 53 analogues of 5-alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4- dihydropyrimidin-4(3$H$)-one for development of models for prediction of anti-HIV-1 activity. A total of 46 2D and 3D molecular descriptors of diverse nature, have been used for decision tree and random forest analysis. The value of majority of these descriptors for each analog... 查看全文

2591   Geochemistry of metasomatic zircons from the Terskii greenstone belt Geochemistry of metasomatic zircons from the Terskii greenstone belt B. Yu. Astaf’ev, S. G. Skublov, V. A. Glebovitskii, I. M. Gembitskaya, O. A. Voinova;O. A. Levchenko    2009 Local isotopic and geochemical studies of the zircons from metasomatites of the Terskii greenstone belt allowed us to determine two stages of metamorphism (2680 and 2025 My) and two stages of metasomatosis (2600 and 1800 My). Almost all the zircons were either metasomatic or affected to some degree by metasomatic processes caused by the enrichment of zircons in light rare earth elements, Th, U, Sr, and Ba, and flattening of the Ce anomaly. 查看全文

2592   Accurate integration of stochastic climate models with application to El Niño Accurate integration of stochastic climate models with application to El Niño    2004 Numerical models are one of the most important theoretical tools in atmospheric research, and the development of numerical techniques specifically designed to model the atmosphere has been an important discipline for many years. In recent years, stochastic numerical models have been introduced in order to investigate more fully Hasselmann's suggestion that the effect of rapidly varying "weather" noise on more slowly varying "climate" could be treated as stochastic forcing. In this article an acc... 查看全文

2593   Statistical modeling of post-heating residual strength for Portland cement concrete Statistical modeling of post-heating residual strength for Portland cement concrete    2007 Strength estimation of concrete in fire-damaged structure enables engineers to propose appropriate repair strategies, if repair is practical and economically visible, or recommend demolishing. In field, strength is estimated either using concrete cores (obtained from damaged members) or through employing certain nondestructive techniques. Concrete coring is destructive and expensive whereas current non-destructive techniques are limited in their ability to detect damage and hence estimate concre... 查看全文

2594   Computing Methods in Applied Sciences and Engineering, Teil I. Intern. Symposium, Versailles, 17.—21. 12. 1973. Ed. Lions, J. L./Glowinski, R., Berlin-Heidelberg-New York. Springer-Verlag. 1974, Computing Methods in Applied Sciences and Engineering, Teil I. Intern. Symposium, Versailles, 17.—21. 12. 1973. Ed. Lions, J. L./Glowinski, R., Berlin-Heidelberg-New York. Springer-Verlag. 1974, Dr. K. H. Beckmann    2006 查看全文

2595   Evolution im Laboratorium Evolution im Laboratorium Dr. K. H. Beckmann    2010 In den letzten 20 Jahren hat sich das Verstndnis der natürlichen Evolution entscheidend gewandelt. Das Darwinsche Konzept von Evolution durch natürliche Selektion wurde auf eine solide physikalische Basis gestellt, welche zu einer Neuinterpretation führte. Evolutive Phnomene wurden zum ersten Male kinetisch quantifizierbar und damit experimentell überprüfbar. Am einfachen Modell der selbstreplizierenden RNA-Moleküle des Qβ-Systems (Qβ ist ein Bakteriophage... 查看全文

2596   Preparation of Bioabsorbable Nerve Guide Tubes Preparation of Bioabsorbable Nerve Guide Tubes Huiguang Zhu, Jian Ji, M. A. Barbosa and Jiacong Shen    2001 Abstract: The use of bioabsorbable polymers in applications as temporary structural function, recovering damage in live tissues, is a promising research area. Membranes of poly(lactic acid) (PLA) may act as support to adhesion and cellular invasion or as devices for guided tissue regeneration (GTR). In this study, the same casting technique used to prepare membranes was used to prepare PLA tubes. These tubes can be used for tests in nerve guided regeneration (NGR). To improve flexibility of the ... 查看全文

2597   Stein und Bein: Biomineralization - Chemical and biochemical perspectives. Hrsg. von S. Mann, J. Webb und R. J. P. Williams. VCH Verlagsgesellschaft, Weinheim 1989. XIV, 541 S., 298 Fig. und 20 Tab., Stein und Bein: Biomineralization - Chemical and biochemical perspectives. Hrsg. von S. Mann, J. Webb und R. J. P. Williams. VCH Verlagsgesellschaft, Weinheim 1989. XIV, 541 S., 298 Fig. und 20 Tab., Neal R. Amundson    2010 查看全文

2598   Ziegler, F.; Schuëller, G. I. (eds.), Nonlinear Stochastic Dynamic Engineering Systems. IUTAM Symposium Innsbruck/Igls, Austria, June 21–26, 1987. Berlin etc., Springer-Verlag 1988. X, 541 Ziegler, F.; Schuëller, G. I. (eds.), Nonlinear Stochastic Dynamic Engineering Systems. IUTAM Symposium Innsbruck/Igls, Austria, June 21–26, 1987. Berlin etc., Springer-Verlag 1988. X, 541    2006 查看全文

2599   Elishakoff, I.; Lin, Y. K. (eds.), Stochastic Structural Dynamics 2 : New Practical Applications. Second International Conference on Stochastic Structural Dynamics 1990, Boca Raton, Florida, USA. Berl Elishakoff, I.; Lin, Y. K. (eds.), Stochastic Structural Dynamics 2 : New Practical Applications. Second International Conference on Stochastic Structural Dynamics 1990, Boca Raton, Florida, USA. Berl    2006 查看全文

2600   Bedford, T.; Swift, J. (eds.), New Directions in Dynamical Systems. Cambridge etc., Cambridge University Press 1988. XIII, 283 pp., £ 17.50. ISBN 0-521-34880-3 (London Mathematical Society Lectu Bedford, T.; Swift, J. (eds.), New Directions in Dynamical Systems. Cambridge etc., Cambridge University Press 1988. XIII, 283 pp., £ 17.50. ISBN 0-521-34880-3 (London Mathematical Society Lectu    2006 查看全文

2601   Electrophoretic Nuclear Magnetic Resonance Studies of Mixed Anionic−Nonionic Surfactant Micelles Electrophoretic Nuclear Magnetic Resonance Studies of Mixed Anionic−Nonionic Surfactant Micelles P. C. Griffiths,*† E. Pettersson,‡ P. Stilbs,‡ A. Y. F. Cheung,† A. M. Howe,§ and A. R. Pitt§    2001 查看全文

2602   SAM investigations of temperature programmed surface segregation of impurities in α-iron SAM investigations of temperature programmed surface segregation of impurities in α-iron B. M. Reichl, M. M. Eisl, T. Weis, H. Hutter;H. Störi    1995 The time development of the surface concentration of impurities such as sulphur and nitrogen in high-purity polycrystalline -iron samples has been investigated by means of Auger Electron Spectroscopy (AES) and Scanning Auger Microscopy (SAM) during linearly increasing the temperature from about 100 to 850°C. The subsequent segregation of N and S revealed strong differences in the segregation kinetics of these elements — especially with respect to the contribution of the dominating tra... 查看全文

2603   Argyris, J.; Mlejnek, H.-P., Die Methode der Finiten Elemente in der elementaren Strukturmechanik. Bd. III: Einführung in die Dynamik. Braunschweig/Wiesbaden, Friedr. Vieweg & Sohn 1988. XXVI Argyris, J.; Mlejnek, H.-P., Die Methode der Finiten Elemente in der elementaren Strukturmechanik. Bd. III: Einführung in die Dynamik. Braunschweig/Wiesbaden, Friedr. Vieweg & Sohn 1988. XXVI    2006 查看全文

2604   Mechanisms controlling activation of the α-globin gene domain in chicken erythroid cells Mechanisms controlling activation of the α-globin gene domain in chicken erythroid cells S. V. Razin;E. S. Ioudinkova    2007 In this review we consider the organization of the chicken α-globin gene domain and mechanisms regulating the activity of this tissue-specific gene domain located in a potentially active (characterized by an increased sensitivity to nucleases) chromatin configuration in cells of all lineages. Both regulatory mechanisms ensuring repression of α-globin genes in non-erythroid cells and mechanisms responsible for activation of transcription of these genes during ery... 查看全文

2605   Using a Causal model for Air Transport Safety (CATS) for the evaluation of alternatives Using a Causal model for Air Transport Safety (CATS) for the evaluation of alternatives    2009 The development of the Netherlands international airport Schiphol has been the subject of fierce political debate for several decades. One of the considerations has been the safety of the population living around the airport, the density of which has been and still is growing. In the debate about the acceptability of the risks associated with the air traffic above The Netherlands extensive use has been made of statistical models relating the movement of airplanes to the risks on the ground. Alth... 查看全文

2606   Finite Elements in Fluids. Vol. 7. Chichester etc., John Wiley & Sons 1988. XI, 314 pp., £ 49.95. ISBN 0-471-91804-0 (Wiley Series in Numerical Methods in Engineering) Finite Elements in Fluids. Vol. 7. Chichester etc., John Wiley & Sons 1988. XI, 314 pp., £ 49.95. ISBN 0-471-91804-0 (Wiley Series in Numerical Methods in Engineering)    2006 查看全文

2607   Schiehlen, W.; Wedig, W. (eds.), Analysis and Estimation of Stochastic Mechanical Systems. Wien-New York, Springer-Verlag 1988. V, 350 pp., 36 figs., öS 504,–/ DM 72,–. ISBN 3–2 Schiehlen, W.; Wedig, W. (eds.), Analysis and Estimation of Stochastic Mechanical Systems. Wien-New York, Springer-Verlag 1988. V, 350 pp., 36 figs., öS 504,–/ DM 72,–. ISBN 3–2    2006 查看全文

2608   Research sampling design for rock lobsters in Te Tapuwae o Rongokako Marine Reserve DOC SCIENCE INTERNAL SERIES 128 Research sampling design for rock lobsters in Te Tapuwae o Rongokako Marine Reserve DOC SCIENCE INTERNAL SERIES 128 John D. Booth    0 Wellington, New ZealandDOC Science Internal Series is a published record of scientific research carried out, or advice given, by Department of Conservation staff, or external contractors funded by DOC. It comprises progress reports and short communications that are generally peer-reviewed within DOC, but not always externally refereed. Fully refereed contract reports funded from the Conservation Services Levy (CSL) are also included. Individual contributions to the series are first released on t... 查看全文

2609   postvectis) in the northern Tararua Ranges Distribution and habitat selection DOC SCIENCE INTERNAL SERIES 30 postvectis) in the northern Tararua Ranges Distribution and habitat selection DOC SCIENCE INTERNAL SERIES 30 Scott Bowie, Ian Henderson    0 Wellington, New ZealandDOC Science Internal Series is a published record of scientific research carried out, or advice given, by Department of Conservation staff, or external contractors funded by DOC. It comprises progress reports and short communications that are generally peer-reviewed within DOC, but not always externally refereed. Fully refereed contract reports funded from the Conservation Services Levy are also included. Individual contributions to the series are first released on the dep... 查看全文

2610   Lewis, R. I., Vortex Element Methods for Fluid Dynamic Analysis of Engineering Systems. Cambridge etc., Cambridge University Press 1991. XXI, 566 pp., L 75.00H/b. ISBN 0-521-36010-2 (Cambridge Engine Lewis, R. I., Vortex Element Methods for Fluid Dynamic Analysis of Engineering Systems. Cambridge etc., Cambridge University Press 1991. XXI, 566 pp., L 75.00H/b. ISBN 0-521-36010-2 (Cambridge Engine    2006 查看全文

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