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292
ON MILD DEGREES OF FLUOROSIS
ON MILD DEGREES OF FLUOROSIS
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J. Moran, R. G. Newcombe, P. Wright, J. Haywood, I. Marlow and M. Addy
2009
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24 recently weaned Sprague-Dawley rats were divided equally into 3 groups and given distilled drinking water ad libitum containing 0, 1 or 5 ppm F- (as NaF), respectively. Among the 13 animals that received the fluoridated water and survived the 2-year experimental period, 4 developed macroradiographically demonstrable resorption cavities in their femurs. Three of these animals belonged to the 1 ppm group. No resorption cavities were seen in the 6 surviving, control rats. There was no sign of to...
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